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Novel endoscopic treatment method for diabetes and obesity from Mannheim being tested nationwide<\/strong><\/p>\n Trans-Duodenal Concepts GmbH started the clinical approval study for its endoscopic implant Trans-Duodenal Barrier<\/strong> on May 4, 2026 following approval by the BfArM and the approval of all responsible ethics committees. The university hospitals in Berlin (Charit\u00e9), Bochum, Heidelberg-Mannheim, Leipzig, W\u00fcrzburg and the hospitals in Bamberg, Dresden and Leipzig (St. Georg) are participating in the study with 125 patients under the direction of Prof. Christoph Reissfelder, Mannheim. <\/p>\n It is intended to demonstrate the effectiveness of the implant in terms of improving diabetes metabolism and weight loss, as well as its safety and tolerability.<\/p>\n The study is being organized by novineon CRO GmbH T\u00fcbingen and supported by the Federal Ministry of Research, Technology and Space.<\/p>\n Obesity, which affects up to 1 billion people worldwide, is associated with numerous secondary diseases such as liver inflammation, cancer, cardiovascular disease and high blood pressure. Type 2 diabetes mellitus plays a special role in this. <\/p>\n Die TDC unter Leitung von Prof. Georg K\u00e4hler ist Entwickler und Hersteller eines endoskopischen Implantates zur nicht-invasiven Therapie von Diabetes und Adipositas. Sie adressiert damit einen der gr\u00f6\u00dften medizinischen M\u00e4rkte mit wachsender sozi\u00f6konomischer Bedeutung. <\/p>\n The principle of an atraumatic reversible endoscopic bypass represents a global innovation and is also attracting great interest worldwide due to its repeatability and combinability with other forms of therapy.<\/p>\n <\/p>\n